منابع مشابه
Neurological involvement in antiphospholipid antibodies syndrome (APS).
Antiphospholipid antibodies (aPL) have been most strongly associated with a syndrome (APS) characterized by venous and/or arterial thrombosis, thrombocytopenia, recurrent fetal losses and a variety of non-thrombotic and thrombotic neurological disorders. Cerebral ischemia associated with aPL is the most common arterial thrombotic manifestation. Other neurological syndromes, such as cognitive dy...
متن کاملPathogenic Mechanisms of Thrombosis in Antiphospholipid Syndrome (APS)
The term "antiphospholipid syndrome" (APS) was coined in the early '80s to describe a unique form of acquired autoimmune thrombophilia, with clinical features of recurrent thrombosis and pregnancy morbidity, combined with the presence of antiphospholipid antibodies (aPL). aPL consist a heterogeneous group of autoantibodies, which recognize phospholipid-protein complexes or rather proteins with ...
متن کاملAntiphospholipid Antibodies and APS Nephropathy
The presence of pathogenic antiphospholipid antibodies (aPL) is the characterizing feature of the antiphospholipid syndrome (APS), mediating the recurrent pregnancy loss and thrombosis typical of the disease through its action on various antigenic targets. APS nephropathy is the characteristic clinico-pathological manifestation of renal involvement in APS and occurs as a result of vaso-occlusiv...
متن کاملSevere Abdominal Pain as a Presenting Symptom of Probable Catastrophic Antiphospholipid Syndrome abstract Catastrophic antiphospholipid syndrome (APS) in pediatric medicine
Catastrophic antiphospholipid syndrome (APS) in pediatric medicine is rare. We report 3 adolescents who presented with acute onset of severe abdominal pain as the first manifestation of probable catastrophic APS. The 3 patients, 2 male patients and 1 female patient were 14 to 18 years old. One had been diagnosed with systemic lupus erythematosus in the past, but the other 2 had no previous rele...
متن کاملInternational consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).
New clinical, laboratory and experimental insights, since the 1999 publication of the Sapporo preliminary classification criteria for antiphospholipid syndrome (APS), had been addressed at a workshop in Sydney, Australia, before the Eleventh International Congress on antiphospholipid antibodies. In this document, we appraise the existing evidence on clinical and laboratory features of APS addre...
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ژورنال
عنوان ژورنال: The Open Urology & Nephrology Journal
سال: 2015
ISSN: 1874-303X
DOI: 10.2174/1874303x01508010001